PXD033153 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Dysregulated proteins in aqueous humor from primary open angle glaucoma patients with clinical correlation |
Description | Primary open angle glaucoma (POAG) presents as an irreversible optic neuropathy with corresponding visual field deficits and no other notable symptoms. The pathophysiology of POAG remains poorly understood. Through proteomic analysis of aqueous humour (AH) from POAG patients, we aim to identify changes in protein composition of these samples compared to control samples. This enables us to better understand pathological changes in POAG from a molecular perspective, and may reveal potential diagnostic molecular biomarkers in POAG. We are also interested in correlating differences in AH protein compositions with demographics and clinical severity in POAG patients. |
HostingRepository | PRIDE |
AnnounceDate | 2024-05-23 |
AnnouncementXML | Submission_2024-05-23_00:13:05.012.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | SoFong Cam Ngan |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-04-11 03:04:27 | ID requested | |
⏵ 1 | 2024-05-23 00:13:05 | announced | |
Publication List
10.1016/j.exer.2024.109887; |
Choy DMY, Ang BCH, Adav SS, Zheng YB, Goh CJS, Wei J, Kumaran A, Chua CH, Gan NY, Sze SK, Yip LWL, Aqueous humour protein dysregulation in Asian eyes with primary open angle glaucoma. Exp Eye Res, 243():109887(2024) [pubmed] |
Keyword List
submitter keyword: proteomics, TMT,primary open angle glaucoma, aqueous humor, LC-MS/MS |
Contact List
Darren Choy Mun Yoong |
contact affiliation | Ophthalmology, Tan Tock Seng Hospital, Singapore |
contact email | darren.choy@mohh.com.sg |
lab head | |
SoFong Cam Ngan |
contact affiliation | Nanyang Technological University |
contact email | sfcngan@ntu.edu.sg |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD033153 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033153
- Label: PRIDE project
- Name: Dysregulated proteins in aqueous humor from primary open angle glaucoma patients with clinical correlation