PXD033069 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Batten's Disease proteomics using iTRAQ LC-MS/MS |
| Description | Proteomic analysis using iTRAQ technique to identify global changes in Batten's disease samples using iPSCs derived from keratinocytes and differentiated to iNPCs Three separate mass spectrometry runs were carried out and results were combined using seaMASS and Bayesian analysis |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-10 |
| AnnouncementXML | Submission_2025-11-09_16:52:38.797.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Aseel Sharaireh |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | iTRAQ8plex-116 reporter+balance reagent acylated residue |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2022-04-07 03:34:14 | ID requested | |
| ⏵ 1 | 2025-11-09 16:52:39 | announced | |
Publication List
| 10.1038/s41419-025-08063-4; |
| Sharaireh A, Guevara-Ferrer M, Ludlaim AM, Humphries JD, Phillips AM, Dowsey AW, Zhang Z, Counsell JR, Unwin RD, Mole SE, Rahim AA, McKay TR, CLN7 protein functions at the interface between endolysosomes and stress granules to promote cell survival. Cell Death Dis, 16(1):772(2025) [pubmed] |
Keyword List
| submitter keyword: CLN7,iPSCs, Battens, NPCs, Proteomics |
Contact List
| Tristan R McKay |
|---|
| contact affiliation | 1Centre for Bioscience, Manchester Metropolitan University, Manchester, UK |
| contact email | t.mckay@mmu.ac.uk |
| lab head | |
| Aseel Sharaireh |
|---|
| contact affiliation | Assistant Professor |
| contact email | a.sharaireh@ju.edu.jo |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD033069 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033069
- Label: PRIDE project
- Name: Batten's Disease proteomics using iTRAQ LC-MS/MS
