PXD032902 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Combining recombinase-mediated cassette exchange strategy with quantitative proteomic and phosphoproteomic analyses to inspect intracellular functions of the tumor supressor galectin-4 in colorectal cancer cells. |
Description | In order to systematically explore Galectin-4 function in CRC we established a CRC cell line where Gal4 expression can be regulated via doxycycline (dox)-inducible expression of a single copy wildtype LGALS4 transgene generated by recombinase-mediated cassette exchange (RMCE). Using this model and applying in depth proteomic and phosphoproteomic analyses we systematically screened for intracellular changes induced by Gal4 expression by. |
HostingRepository | PRIDE |
AnnounceDate | 2022-08-12 |
AnnouncementXML | Submission_2022-08-12_00:10:45.581.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Malwina Michalak |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-04-02 10:31:56 | ID requested | |
⏵ 1 | 2022-08-12 00:10:46 | announced | |
Publication List
Michalak M, Golde V, Helm D, Kaltner H, Gebert J, Kopitz J, Combining Recombinase-Mediated Cassette Exchange Strategy with Quantitative Proteomic and Phosphoproteomic Analyses to Inspect Intracellular Functions of the Tumor Suppressor Galectin-4 in Colorectal Cancer Cells. Int J Mol Sci, 23(12):(2022) [pubmed] |
Keyword List
submitter keyword: Galectin, Colorectal Cancer |
Contact List
Juergen Kopitz |
contact affiliation | Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital |
contact email | Juergen.Kopitz@med.uni-heidelberg.de |
lab head | |
Malwina Michalak |
contact affiliation | Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital |
contact email | malwina.michalak@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD032902
- Label: PRIDE project
- Name: Combining recombinase-mediated cassette exchange strategy with quantitative proteomic and phosphoproteomic analyses to inspect intracellular functions of the tumor supressor galectin-4 in colorectal cancer cells.