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PXD032743-3

PXD032743 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBinding partners of FAM134B WT and 17KR oligomers
DescriptionFAM134B is a reticulon-homology domain (RHD)-containing protein that participates in membrane-shaping of the endoplasmic reticulum (ER)8 13. It also functions as a mammalian ER-phagy receptor, mediating the fragmentation and selective degradation of ER sheets in multiple cell types8. However, little is known about the molecular and biophysical mechanisms that control and/or switch between these two FAM134B functions.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:48:53.146.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAdriana Covarrubias-Pinto
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-03-23 07:30:48ID requested
12023-06-19 06:48:09announced
22023-11-14 09:01:25announced2023-11-14: Updated project metadata.
32024-10-22 05:48:53announced2024-10-22: Updated project metadata.
Publication List
10.1038/s41586-023-06089-2;
Gonz, á, lez A, Covarrubias-Pinto A, Bhaskara RM, Glogger M, Kuncha SK, Xavier A, Seemann E, Misra M, Hoffmann ME, Br, ä, uning B, Balakrishnan A, Qualmann B, D, ö, tsch V, Schulman BA, Kessels MM, H, ü, bner CA, Heilemann M, Hummer G, Diki, ć I, Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum. Nature, 618(7964):394-401(2023) [pubmed]
Keyword List
submitter keyword: Venus FAM134B WT and 17 KR
Contact List
Ivan Dikic
contact affiliationInstitute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue Straße 15, 60438 Frankfurt am Main, Germany
contact emaildikic@biochem2.uni-frankfurt.de
lab head
Adriana Covarrubias-Pinto
contact affiliationGoethe University
contact emailCovarrubiasPinto@med.uni-frankfurt.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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