PXD032234-2

PXD032234 is an original dataset announced via ProteomeXchange.

Title	Cellular and culture medium proteomes from umbilical cord mesenchymal stem cell and human umbilical vein endothelial cells
Description	Application of umbilical cord mesenchymal stem cell-derived conditioned media (HUCMSC-CM) to treat severe, progressive PAH. Serial infusions of HUCMSC-CM resulted in marked clinical and hemodynamic improvement after 6 months, and showed no adverse events. Differential expression analysis between conditioned media and cells was used to identify molecular processes with a putative role in treatment benefit.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:35:32.610.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Michael Mülleder
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	timsTOF Pro 2

Revision	Datetime	Status	ChangeLog Entry
0	2022-03-11 10:49:51	ID requested
1	2022-05-04 05:15:56	announced
⏵ 2	2023-11-14 07:35:33	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: Human, PAH,HUCMSC, HUVEC

Prof. Dr. Georg Hansmann
contact affiliation	Department of Pediatric Cardiology and Critical Care; Pulmonary Vascular Research Center; Hannover Medical School; Hannover; Germany
contact email	hansmann.georg@mh-hannover.de
lab head
Michael Mülleder
contact affiliation	Core Facility -High-Throughput Mass Spectrometry, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health (BIH), Berlin, Germany
contact email	michael.muelleder@charite.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/11/PXD032234

PRIDE project URI

• PRIDE
  1. PXD032234
     1. Label: PRIDE project
     2. Name: Cellular and culture medium proteomes from umbilical cord mesenchymal stem cell and human umbilical vein endothelial cells