PXD032063 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Detecting mistranslation from a serine tRNA with proline anticodon expressed in yeast |
Description | Mistranslation, the mis-incorporation of an amino acid not specified by the “standard” genetic code, occurs in all cells. tRNA variants that increase mistranslation arise spontaneously and engineered tRNAs can achieve mistranslation frequencies approaching 10% in yeast and bacteria. The goal of this study was to detect and quantify mistranslation from a serine tRNA variant with proline UGG anticodon and G26A secondary mutation engineered in yeast |
HostingRepository | PRIDE |
AnnounceDate | 2022-08-12 |
AnnouncementXML | Submission_2022-08-12_00:01:24.563.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Matthew Berg |
SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-03-04 09:32:23 | ID requested | |
⏵ 1 | 2022-08-12 00:01:25 | announced | |
Publication List
Berg MD, Zhu Y, Loll-Krippleber R, San Luis BJ, Genereaux J, Boone C, Vill, é, n J, Brown GW, Brandl CJ, Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG. G3 (Bethesda), 12(7):(2022) [pubmed] |
Keyword List
submitter keyword: Yeast, mistranslation, tRNA |
Contact List
Judit Villen |
contact affiliation | Department of Genome Sciences, University of Washington, Seattle, USA |
contact email | jvillen@uw.edu |
lab head | |
Matthew Berg |
contact affiliation | Department of Genome Sciences, University of Washington |
contact email | mattberg@uw.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD032063 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD032063
- Label: PRIDE project
- Name: Detecting mistranslation from a serine tRNA with proline anticodon expressed in yeast