PXD032022-2
PXD032022 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The role and mechanism of METTL16 in Alzheimer's disease |
| Description | Mettl16 regulates SAM homeostasis by mediating m6A modification of MAT2A mRNA and participates in the pathogenesis of Alzheimer's disease. |
| HostingRepository | iProX |
| AnnounceDate | 2022-03-03 |
| AnnouncementXML | Submission_2023-02-02_19:02:31.831.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Runjiao Zhang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | TMT quantitation analysis |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2022-03-02 22:25:13 | ID requested | |
| 1 | 2022-03-02 22:25:26 | announced | |
| ⏵ 2 | 2023-02-02 19:02:32 | announced | 2023-02-03: Update publication information. |
Publication List
| Zhang R, Zhang Y, Guo F, Huang G, Zhao Y, Chen B, Wang C, Cui C, Shi Y, Li S, Cui H, Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA. Cell Death Discov, 8(1):432(2022) [pubmed] |
Keyword List
| submitter keyword: N6-methyladenosine (m6A), METTL16, MAT2A, SAM, Alzheimer's disease. |
Contact List
| Huixian Cui | |
|---|---|
| contact affiliation | Hebei Medical University |
| contact email | cuihxhebmu@126.com |
| lab head | |
| Runjiao Zhang | |
| contact affiliation | Hebei Medical University |
| contact email | zhangrunjiao111@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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