PXD031714 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Nuclear F-actin Assembly on Damaged Chromatin is Regulated By DYRK1A and Spir1 Phosphorylation |
Description | The uploaded data are described within "DYRK1A promotes nuclear F-actin assembly to effect DSB repair metabolism". Peptides from RPE1 epithelial cells with either, over expression of DYRK1A, normal expression of DYRK1A, or knockout of DYRK1A were labeled with TMTpro-16 reagents and phosphopeptides enriched by TiO2 and Fe-NTA resins. |
HostingRepository | PRIDE |
AnnounceDate | 2024-07-19 |
AnnouncementXML | Submission_2024-07-19_11:08:22.022.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Kirk West |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | Orbitrap Eclipse |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-02-16 04:44:14 | ID requested | |
⏵ 1 | 2024-07-19 11:08:22 | announced | |
Publication List
10.1093/nar/gkae574; |
Li J, Xiong N, West KL, Leung M, Ching YP, Huang J, Yuan J, Yu CH, Leung J, Huen M, Nuclear F-actin assembly on damaged chromatin is regulated by DYRK1A and Spir1 phosphorylation. Nucleic Acids Res, 52(15):8897-8912(2024) [pubmed] |
Keyword List
submitter keyword: DYRK1A |
DSB repair |
Spir1 |
DSB mobility |
Actin Dynamics |
Contact List
Justin Wai |
contact affiliation | Department of Radiation Oncology, University of Texas Health Science Center at San Antonio |
contact email | JWLeung@uams.edu |
lab head | |
Kirk West |
contact affiliation | University of Arkansas for Medical Sciences |
contact email | kwest@uams.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD031714 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD031714
- Label: PRIDE project
- Name: Nuclear F-actin Assembly on Damaged Chromatin is Regulated By DYRK1A and Spir1 Phosphorylation