PXD031652-1

PXD031652 is an original dataset announced via ProteomeXchange.

Title	Integration of Urine Proteomic and Metabolomic profiling Reveals Novel Insights into Neuroimmune Dysfunction in Autism Spectrum Disorder
Description	Autism spectrum disorder (ASD) is a complex set of neurodevelopmental diseases. However, the etiology and pathogenesis of ASD is largely unknown. An integrated proteomics and metabolomics approach was performed on urine sampled from diagnosed ASD children and typical children. All urine protein samples (n= 160) were subjected to data-independent acquisition proteomic analysis and 60 urine samples underwent liquid chromatography-mass spectrometry based on metabolomic analysis. So, this study presents an overview of the molecular mechanism of ASD and offers some potential targets for further early screening.
HostingRepository	iProX
AnnounceDate	2022-02-11
AnnouncementXML	Submission_2022-02-13_18:13:24.491.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wenlong Liu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-02-13 18:11:39	ID requested
⏵ 1	2022-02-13 18:13:24	announced
2	2022-10-08 19:45:02	announced	2022-10-09: Update publication information.

Dataset with its publication pending

submitter keyword: Children, Autism spectrum disorder, Urine, Proteomics

Juan Wang
contact affiliation	Department of Public Health and Medical Technology, Xiamen Medical College
contact email	wang112976juan@xmmc.edu.cn
lab head
Wenlong Liu
contact affiliation	Women and Children's Hospital, School of Medicine, Xiamen University
contact email	wenlongliu2005@163.com
dataset submitter

iProX dataset URI