⮝ Full datasets listing
PXD031209-2
PXD031209 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Oxygen-sensitive methylation of ULK1 is required for hypoxia-induced autophagy |
| Description | Hypoxia is a physiological stress that frequently occurs in solid tissues. Autophagy, a ubiquitous degradation/recycling system in eukaryotic cells, renders cells tolerant to multiple stressors. However, the mechanisms underlying autophagy initiation upon hypoxia remains unclear. This study identifies an oxygen-sensitive methylation of ULK1 with an important role in hypoxic stress adaptation by promoting autophagy induction. |
| HostingRepository | iProX |
| AnnounceDate | 2022-01-25 |
| AnnouncementXML | Submission_2022-10-08_23:51:19.834.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Rui Liu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | phosphorylated residue; dimethylated residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2022-01-24 21:18:27 | ID requested | |
| 1 | 2022-01-25 19:19:19 | announced | |
| ⏵ 2 | 2022-10-08 23:51:20 | announced | 2022-10-09: Update publication information. |
Publication List
| Li J, Zhang T, Ren T, Liao X, Hao Y, Lim JS, Lee JH, Li M, Shao J, Liu R, Oxygen-sensitive methylation of ULK1 is required for hypoxia-induced autophagy. Nat Commun, 13(1):1172(2022) [pubmed] |
Keyword List
| submitter keyword: ULK1 , hypoxia |
Contact List
| Rui Liu | |
|---|---|
| contact affiliation | Proteomics and Metabolomics Platform, the state key lab of oral diseases, Sichuan University |
| contact email | liurui_scu@hotmail.com |
| lab head | |
| Rui Liu | |
| contact affiliation | The state key lab of oral diseases, Sichuan University |
| contact email | liurui_scu@hotmail.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
