PXD031033-3

PXD031033 is an original dataset announced via ProteomeXchange.

Title	Cross-linking MS of S. cerevisiae ORC bound to DNA and Cdc6
Description	During DNA replication initiation, the Origin Recognition Complex (ORC) and Cdc6 co-associate on DNA to load replicative helicases onto origins of replication. We apply DSSO crosslinking mass spectrometry of reconstituted ORC-DNA-Cdc6 to identify interactions between different subunits and domains in the complex.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:33:49.682.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jan Seebacher
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2022-01-17 08:53:55	ID requested
1	2022-02-28 01:21:21	announced
2	2023-11-14 08:54:48	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:33:50	announced	2024-10-22: Updated project metadata.

10.1038/S41467-022-28695-W;

submitter keyword: cleavable, CID,XLMS, Xlinkx, crosslinking MS, DSSO, phosphorylation, MS2_MS3, ORC

Franziska Bleichert
contact affiliation	Department of Molecular Biophysics and Biochemistry, Bleichert lab, Yale University, USA
contact email	franziska.bleichert@yale.edu
lab head
Jan Seebacher
contact affiliation	FMI Basel
contact email	jan.seebacher@fmi.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD031033

PRIDE project URI

• PRIDE
  1. PXD031033
     1. Label: PRIDE project
     2. Name: Cross-linking MS of S. cerevisiae ORC bound to DNA and Cdc6