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PXD030947-1

PXD030947 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSWATH-MS identification of CXCL7, LBP, TGFβ1 and PDGFRβ as novel biomarkers in human systemic mastocytosis.
DescriptionWe carried out a novel clinical biomarker investigation of the blood of systemic mastocytosis patients versus healthy controls; utilizing a new and emerging technology platform Sequential Window Acquisition of all Theoretical fragment-ion spectra mass spectrometry (SWATH-MS). This is the first use of this novel proteomic technique in the study of mastocytosis. A Swath-MS based biomarkers dsicovery study for systemic mastocytosis with orthogonal validation of biomarkers via ELISA.
HostingRepositoryPRIDE
AnnounceDate2022-05-20
AnnouncementXMLSubmission_2022-05-20_06:49:03.482.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterbobby graham
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 6600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-01-14 00:32:30ID requested
12022-05-20 06:49:04announced
Publication List
Graham RLJ, McMullen AA, Moore G, Dempsey-Hibbert NC, Myers B, Graham C, as novel biomarkers in human systemic mastocytosis. Sci Rep, 12(1):5087(2022) [pubmed]
Keyword List
submitter keyword: Swath-MS, Biomarkers, Mastocytosis
Contact List
Dr Ciaren Graham
contact affiliationDeputy Head of School, School of Biological Sciences | 19 Chlorine Gardens| Belfast, BT9 5DJ Queen’s University Belfast | +44 28 9097 2383 | https://www.qub.ac.uk/schools/SchoolofBiologicalSciences/
contact emailciaren.graham@qub.ac.uk
lab head
bobby graham
contact affiliationQueens University Belfast
contact emailr.graham@qub.ac.uk
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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