PXD030180 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomics of KRAS mutated and non-transformed pancreas cells treated with ethanol |
Description | The goal for this study was to determine the effects of ethanol on pancreas cells and examine how ethanol influences protein expression in non-transformed and mutant KRAS cells. We performed TMT-labeled proteomics of non-transformed (hTERT-HPNE E6/E7) and KRAS mutated (hTERT-HPNE E6/E7/K-RasG12D) human pancreas cell lines following 6 months of 100 mM ethanol treatment. |
HostingRepository | PRIDE |
AnnounceDate | 2022-05-19 |
AnnouncementXML | Submission_2022-05-19_06:09:24.264.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Emalie Clement |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-12-05 04:32:36 | ID requested | |
⏵ 1 | 2022-05-19 06:09:25 | announced | |
Publication List
Clement EJ, Law HC, Qiao F, Noe D, Trevino JG, Woods NT, Combined Alcohol Exposure and KRAS Mutation in Human Pancreatic Ductal Epithelial Cells Induces Proliferation and Alters Subtype Signatures Determined by Multi-Omics Analysis. Cancers (Basel), 14(8):(2022) [pubmed] |
Keyword List
submitter keyword: Ethanol, KRAS, TMT, Pancreas |
Contact List
Nicholas T. Woods |
contact affiliation | University of Nebraska Medical Center |
contact email | nicholas.woods@unmc.edu |
lab head | |
Emalie Clement |
contact affiliation | UNMC |
contact email | emalie.clement@unmc.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD030180 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD030180
- Label: PRIDE project
- Name: Proteomics of KRAS mutated and non-transformed pancreas cells treated with ethanol