PXD030144-2
PXD030144 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Requirement of Rbx1 Cullin-RING ligase E3 and Ube2m neddylation E2 in the maintenance of the fitness of Treg cells |
| Description | the Ube2m-Rbx1 axis is required for the maintenance of homeostasis and functions of Treg cells; and Rbx1 has Ube2m-independent roles in the fitness of Treg cells, suggesting a layer of complexity in neddylation activation of CRLs. |
| HostingRepository | iProX |
| AnnounceDate | 2021-12-03 |
| AnnouncementXML | Submission_2022-10-12_19:42:47.420.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Mingwei Liu |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2021-12-02 20:03:35 | ID requested | |
| 1 | 2021-12-02 20:07:26 | announced | |
| ⏵ 2 | 2022-10-12 19:42:48 | announced | 2022-10-13: Update publication information. |
Publication List
| Wu D, Li H, Liu M, Qin J, Sun Y, The Ube2m-Rbx1 neddylation-Cullin-RING-Ligase proteins are essential for the maintenance of Regulatory T cell fitness. Nat Commun, 13(1):3021(2022) [pubmed] |
Keyword List
| submitter keyword: Rbx1, Treg cells, mice |
Contact List
| Yi Sun | |
|---|---|
| contact affiliation | Institute of Translational Medicine, Zhejiang University School of Medicine |
| contact email | yisun@zju.edu.cn |
| lab head | |
| Mingwei Liu | |
| contact affiliation | Beijing Proteome Research Center |
| contact email | mwliu@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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