PXD030011-2

PXD030011 is an original dataset announced via ProteomeXchange.

Title	Pancreatic ductal adenocarcinoma (PDAC) ubiquitination profiling reveals specific prognostic and theranostic markers.
Description	The project was aimed at identifying diGlycine (diGly) conjugated peptides obtained from sixty PDACs' patients' derived xenografs (PDXs) then to identify potential diGLy profiles that could be used as prognosis markers of the aggressiveness of the tumour and overall survival of patients as well as theranostic makers able to predict tumour sensitivity to the different chemotherapeutic drugs commonly used to treat this form of cancer.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:03:56.277.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	AUDEBERT Stephane
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	ubiquitination signature dipeptidyl lysine; monohydroxylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-28 05:57:21	ID requested
1	2023-07-20 12:33:36	announced
⏵ 2	2023-11-14 09:03:57	announced	2023-11-14: Updated project metadata.
3	2024-10-22 05:57:02	announced	2024-10-22: Updated project metadata.

El Kaoutari A, Fraunhoffer NA, Audebert S, Camoin L, Berthois Y, Gayet O, Roques J, Bigonnet M, Bongrain C, Ciccolini J, Iovanna JL, Dusetti NJ, Soubeyran P, Pancreatic ductal adenocarcinoma ubiquitination profiling reveals specific prognostic and theranostic markers. EBioMedicine, 92():104634(2023) [pubmed]

submitter keyword: theranostic markers., Ubiquitinome, diGLy peptide profiling, prognostic markers,LC-MSMS, PDAC

Philippe Soubeyran, PhD
contact affiliation	Centre de Recherche en Cancérologie de Marseille, Inserm UMR1068 Parc Scientifique et Technologique de Luminy 163, Avenue de Luminy Case 915 13288 Marseille Cedex 9 FRANCE
contact email	philippe.soubeyran@inserm.fr
lab head
AUDEBERT Stephane
contact affiliation	Marseille Proteomic, Centre de Recherche en Cancérologie de Marseille, Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli Calmettes, 27 Boulevard Leï Roure CS30059 13273 Marseille Cedex 09 France
contact email	stephane.audebert@inserm.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD030011

PRIDE project URI

• PRIDE
  1. PXD030011
     1. Label: PRIDE project
     2. Name: Pancreatic ductal adenocarcinoma (PDAC) ubiquitination profiling reveals specific prognostic and theranostic markers.