PXD029962-1

PXD029962 is an original dataset announced via ProteomeXchange.

Title	Proteomics of AT2 cells constitutively expressing surfactant protein SP-C(I73T)
Description	This project has the goal of determine the impact of the missense mutation I73T on the surfactant protein SP-C and the role of EMC3 in regulating the trafficking of this protein.
HostingRepository	PRIDE
AnnounceDate	2024-10-30
AnnouncementXML	Submission_2024-10-30_09:31:35.604.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ernesto Nakayasu
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-26 04:14:28	ID requested
⏵ 1	2024-10-30 09:31:36	announced

Tang X, Wei W, Sun Y, Weaver TE, Nakayasu ES, Clair G, Snowball JM, Na CL, Apsley KS, Martin EP, Kotton DN, Alysandratos KD, Huo J, Molkentin JD, Gower WA, Lin X, Whitsett JA, EMC3 regulates trafficking and pulmonary toxicity of the SFTPCI73T mutation associated with interstitial lung disease. J Clin Invest, ():(2024) [pubmed]

10.1172/jci173861;

submitter keyword: Surfactant Protein C, Human,Lung, trafficking, mutation

Ernesto Nakayasu
contact affiliation	Biological Sciences Division, Pacific Northwest National Laboratory
contact email	ernesto.nakayasu@pnnl.gov
lab head
Ernesto Nakayasu
contact affiliation	Pacific Northwest National Laboratory
contact email	ernesto.nakayasu@pnnl.gov
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD029962

PRIDE project URI

• PRIDE
  1. PXD029962
     1. Label: PRIDE project
     2. Name: Proteomics of AT2 cells constitutively expressing surfactant protein SP-C(I73T)