PXD029837-1

PXD029837 is an original dataset announced via ProteomeXchange.

Title	Partial characterization of the glycoconjugates of Trypanosoma theileri
Description	Here, we have started to characterise the surface molecules of T. theileri at the biochemical level. We have applied the same differential solvent extraction and hydrophobic interaction chromatography protocols, developed by Almeida and colleagues [13,14] to those used to isolate the GPI-mucin and GIPL fractions of T. theileri. As a positive control, we processed epimastigotes of T. cruzi Silvio X10/7 strain alongside tissue culture forms of T. theileri Edinburgh strain and so also report on the surface molecules of the Silvio X10/7 strain of T. cruzi for the first time.
HostingRepository	PRIDE
AnnounceDate	2025-09-29
AnnouncementXML	Submission_2025-09-28_16:04:27.007.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Michele Tinti
SpeciesList	scientific name: Trypanosoma brucei; NCBI TaxID: 5691;
ModificationList	acetylated residue; monohydroxylated residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-20 09:06:43	ID requested
⏵ 1	2025-09-28 16:04:27	announced

10.1016/j.molbiopara.2023.111591;

Nagar R, Hambleton I, Tinti M, Carrington M, Ferguson MAJ, Characterization of the major surface glycoconjugates of Trypanosoma theileri. Mol Biochem Parasitol, 256():111591(2023) [pubmed]

submitter keyword: Trypanosoma theileri, Mucin, Glycoconjugate, Glycoinositol-phospholipids, glycosylphosphatidylinositol, GPI

Professor Sir Mike Ferguson
contact affiliation	Biological Chemistry and Drug Discovery Wellcome Centre for Anti-Infectives Research (WCAIR) University of Dundee, Dundee
contact email	m.a.j.ferguson@dundee.ac.uk
lab head
Michele Tinti
contact affiliation	Dundee University
contact email	m.tinti@dundee.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD029837

PRIDE project URI

• PRIDE
  1. PXD029837
     1. Label: PRIDE project
     2. Name: Partial characterization of the glycoconjugates of Trypanosoma theileri