PXD029732 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | A Clinical trial ready proteomics workflow to support large-scale analysis of Human Plasma: application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial |
Description | Background: Proteomic mass spectrometry is widely used to quantify proteins in biological specimens for biomarker discovery. Clinical studies requiring proteomic analysis of plasma are more complicated due to the high dynamic range and abundance of major plasma proteins. There is an unmet need to develop robust, rapid and cost-effective workflows able to support large-scale clinical studies of thousands of plasma specimens. We set about developing a suitable system to be used for the analysis of plasma collected from FIELD trial participants which investigated five years oral fenofibrate on coronary heart disease and microvascular complications. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:55:39.283.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Matthew O'Rourke |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-11-12 08:01:28 | ID requested | |
1 | 2023-09-29 01:16:33 | announced | |
⏵ 2 | 2023-11-14 08:55:40 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Plasma, DIA, Clinical Trial, Clionical proteomics, Orbitrap |
Contact List
Mark Molloy |
contact affiliation | BIomarker and bowel cancer laboratory, Kolling institute of medical research, university of sydney |
contact email | m.molloy@sydney.edu.au |
lab head | |
Matthew O'Rourke |
contact affiliation | University of Technology Sydney |
contact email | matthew.orourke1@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD029732 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD029732
- Label: PRIDE project
- Name: A Clinical trial ready proteomics workflow to support large-scale analysis of Human Plasma: application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial