PXD029695-1

PXD029695 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Global and targeted metabolomics characterizes antipsychotic medications, amino acid signatures, and platelet-activating factor involvement in first-episode psychosis
Description	We performed global untargeted metabolomics by LCMS using a Q Exactive Focus mass spectrometer coupled to a Dionex U3000 UHPLC of plasma extract from patients following First Episode Psychosis. Both positive and negative reversed phase injections were performed in triplicate with replicates performed in separate batches. The Biocrates p400 kit was also used to obtain absolute quantification of 400+ metabolites using the vendor kit, column, and data processing tools as provided. The resulting global data was processed with Compound Discoverer 2.1. The resulting output is included within this upload as well as the output from the Biocrates data processing software. Data was integrated using a variety of R scripts as detailed in the associated manuscript.
HostingRepository	MassIVE
AnnounceDate	2021-11-12
AnnouncementXML	Submission_2021-11-12_06:22:57.575.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ben Orsburn
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-12 05:16:51	ID requested
⏵ 1	2021-11-12 06:22:57	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Metabolomics, Biocrates p400, schizophrenia, global metabolomics, first episode psychosis

submitter keyword: Metabolomics, Biocrates p400, schizophrenia, global metabolomics, first episode psychosis

Contact List

Benjamin C Orsburn
contact affiliation	Johns Hopkins
contact email	borsbur1@jhmi.edu
lab head
Ben Orsburn
contact affiliation	Johns Hopkins University
contact email	orsburn@vt.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000088371/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000088371/