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PXD029401-1

PXD029401 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleRat parathyroid phosphoproteins LC-MS/MS
DescriptionThe mechanisms of chronic kidney disease-associated secondary hyperparathyroidism are partially understood. In this project we aimed to gain new information and propose research hypotheses by proteome and phosphoproteome profiling of normal and hyperplastic rat parathyroid glands. Glands were microdissected from rats on normal control diet or CKD-inducing high adenine diet enriched with phosphorus to produce secondary hyperparathyroidism. Protein extracts were pooled from 12 glands (6 rats) for phosphoproteome profiling (3 normal and 3 CKD pools).
HostingRepositoryPRIDE
AnnounceDate2022-06-28
AnnouncementXMLSubmission_2022-06-28_05:49:06.204.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterIddo Ben-Dov
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListphosphorylated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-10-28 06:42:01ID requested
12022-06-28 05:49:06announced
22023-11-14 08:53:53announced2023-11-14: Updated project metadata.
Publication List
10.1681/ASN.2022020197;
Keyword List
submitter keyword: Rat, parathyroid, phosphoproteins, LC-MS/MS, secondary hyperparathyroidism, chronic kidney disease
Contact List
Iddo Zeev Ben-Dov
contact affiliationHadassah - Hebrew University Medical Center, Department of Nephrology and Hypertension
contact emailiddobe@ekmd.huji.ac.il
lab head
Iddo Ben-Dov
contact affiliationHadassah - Hebrew University Medical Center
contact emailiddobe@ekmd.huji.ac.il
dataset submitter
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Dataset FTP location
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