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PXD029341-1
PXD029341 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The IPF fibroblastic focus is an active collagen biosynthesis factory embedded in a distinct extracellular matrix |
| Description | The Fibroblastic Focus (FF) is a lesion typical of Idiopathic Pulmonary Fibrosis (IPF). It is the site of myofibroblast accumulation and extracellular matrix (ECM) production. The molecular composition and function of the FF and surrounding tissue remain undefined. Utilizing laser capture microdissection coupled mass spectrometry (LCM-MS), we interrogate the FF, adjacent mature scar tissue, and adjacent alveoli in 6 IPF specimens. To serve as a control, we perform LCM-MS on alveoli from 6 non-fibrotic controls. |
| HostingRepository | PRIDE |
| AnnounceDate | 2022-08-31 |
| AnnouncementXML | Submission_2022-08-31_04:52:46.392.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Craig Lawless |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2021-10-25 06:48:20 | ID requested | |
| ⏵ 1 | 2022-08-31 04:52:47 | announced |
Publication List
Keyword List
| submitter keyword: Human, IPF, Collagen, fibroblastic focus |
Contact List
| Jeremy Herrera | |
|---|---|
| contact affiliation | The Wellcome Centre for Cell-Matrix Research, University of Manchester, Manchester, UK |
| contact email | Jeremy.Herrera@manchester.ac.uk |
| lab head | |
| Craig Lawless | |
| contact affiliation | University of Manchester |
| contact email | craig.lawless@manchester.ac.uk |
| dataset submitter | |
Full Dataset Link List
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD029341 |
| PRIDE project URI |
Repository Record List
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