PXD029189-1

PXD029189 is an original dataset announced via ProteomeXchange.

Title	GPI-glycan structures of Prion from PGAP4-KO mouse brains
Description	To determine glycosylphosphatidylinositol (GPI) structures of prion proteins isolated from PGAP4-KO mouse brains.
HostingRepository	PRIDE
AnnounceDate	2022-05-25
AnnouncementXML	Submission_2022-05-25_05:06:00.523.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tetsuya Hirata
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-18 01:57:30	ID requested
⏵ 1	2022-05-25 05:06:01	announced

Hirata T, Kobayashi A, Furuse T, Yamada I, Tamura M, Tomita H, Tokoro Y, Ninomiya A, Fujihara Y, Ikawa M, Maeda Y, Murakami Y, Kizuka Y, Kinoshita T, Loss of the N-acetylgalactosamine side chain of the GPI-anchor impairs bone formation and brain functions and accelerates the prion disease pathology. J Biol Chem, 298(3):101720(2022) [pubmed]

submitter keyword: GPI, GPI side chain, Mouse, Prion, Brain

Taroh Kinoshita
contact affiliation	Research Institute for Microbial Diseases, Osaka University
contact email	tkinoshi@biken.osaka-u.ac.jp
lab head
Tetsuya Hirata
contact affiliation	Center for Highly Advanced Integration of Nano and Life Sciences (G-CHAIN)
contact email	hirata01@gifu-u.ac.jp
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD029189

PRIDE project URI

• PRIDE
  1. PXD029189
     1. Label: PRIDE project
     2. Name: GPI-glycan structures of Prion from PGAP4-KO mouse brains