PXD029071 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Transglutaminase 3 crosslinks MUC2 and stabilizes the colonic mucus layer |
Description | Mucus/MUC2 from TGM3-deficient mice is less cross-linked with isopeptide-bond cross-links compared to Mucus/MUC2 from WT mice. This results in protease-labile MUC2-molecules that become degraded in the colonic lumen |
HostingRepository | PRIDE |
AnnounceDate | 2022-02-09 |
AnnouncementXML | Submission_2022-02-09_07:52:00.794.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Christian Recktenwald |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-10-12 03:22:37 | ID requested | |
⏵ 1 | 2022-02-09 07:52:01 | announced | |
2 | 2023-04-11 06:34:36 | announced | 2023-04-11: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Mucus, MUC2, transglutaminase |
Contact List
Gunnar Claes Hansson |
contact affiliation | University of Gothenburg Institute of Biomedicine Department of Medical Biochemistry Mucin Biology Groups Sweden |
contact email | gunnar.hansson@medkem.gu.se |
lab head | |
Christian Recktenwald |
contact affiliation | Department of Medical Biochemistry University of Gothenburg |
contact email | christian.recktenwald@medkem.gu.se |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD029071 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD029071
- Label: PRIDE project
- Name: Transglutaminase 3 crosslinks MUC2 and stabilizes the colonic mucus layer