PXD028978 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis of human SKBR3/HER2+ breast cancer cell-surface proteins by using tryptic shaving |
Description | The plasma membrane proteome resides at the interface between the extra- and intra-cellular environment and through its various roles in signal transduction, immune recognition, nutrient transport, and cell-cell and cell-matrix interactions plays a critical role in determining the fate of a cell. The objective of this study was to characterize the cell-membrane proteome of SKBR3/HER2+ breast cancer cells by using mass spectrometry detection, to advance the understanding of biological triggers that sustain aberrant cell survival, proliferation, and development of resistance to therapeutic drugs. |
HostingRepository | PRIDE |
AnnounceDate | 2022-07-11 |
AnnouncementXML | Submission_2022-07-11_07:47:04.265.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Arba Karcini |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-10-07 00:27:27 | ID requested | |
⏵ 1 | 2022-07-11 07:47:04 | announced | |
2 | 2023-11-14 08:53:08 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: SKBR3 cells, cancer, cell-surface proteins |
Contact List
Iulia M. Lazar |
contact affiliation | Virginia Tech, Biological Sciences |
contact email | malazar@vt.edu |
lab head | |
Arba Karcini |
contact affiliation | Virginia Tech |
contact email | akarcini@vt.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD028978 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD028978
- Label: PRIDE project
- Name: Proteomic analysis of human SKBR3/HER2+ breast cancer cell-surface proteins by using tryptic shaving