PXD028960 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | In vivo BioID Mouse heart masspec data |
Description | Cardiac excitation-contraction (E-C) coupling requires dyads, the nanoscopic microdomains formed adjacent to Z-lines by apposition of transverse (T)-tubules and junctional sarcoplasmic reticulum (jSR). Disruption of dyad architecture and function are common features of diseased cardiomyocytes. However, little is known about the mechanisms that modulate dyad organization during cardiac homeostasis and disease. Here, we used proximity proteomics in intact, living hearts to identify proteins enriched near dyads. |
HostingRepository | PRIDE |
AnnounceDate | 2022-02-21 |
AnnouncementXML | Submission_2022-02-21_09:21:22.122.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD028960 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Fujian Lu |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | biotinylated residue |
Instrument | LTQ; LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-10-06 04:19:08 | ID requested | |
⏵ 1 | 2022-02-21 09:21:22 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Mouse hearts, BioID, RyR2, Ca signaling |
Contact List
William T. Pu |
contact affiliation | Department of Cardiology Boston Children's Hospital |
contact email | william.pu@cardio.chboston.org |
lab head | |
Fujian Lu |
contact affiliation | Boston Children's Hospital |
contact email | fujian.lu@childrens.harvard.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD028960
- Label: PRIDE project
- Name: In vivo BioID Mouse heart masspec data