PXD028950 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Impact of fetal growth restriction on neonatal microglia proteome in rat. |
Description | Microglia activation is a key modulator of brain vulnerability in response to intra-uterine growth restriction (IUGR). However, the consequences of IUGR on microglia development and on microglia proteome are still unknown. We used a model of IUGR induced by a gestational low-protein diet (LPD) in rat. Microglia were isolated from control and LPD animals at P1 and P4. The aim of this work was characterize the consequence of IUGR on microglia development and investigate the consequences of IUGR exposure on microglia proteome during the first postnatal days using a bioinformatics approach associated with functional assays. |
HostingRepository | PRIDE |
AnnounceDate | 2021-12-17 |
AnnouncementXML | Submission_2021-12-17_07:13:40.575.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Virginie Salnot |
SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-10-05 05:41:43 | ID requested | |
⏵ 1 | 2021-12-17 07:13:41 | announced | |
Publication List
Zinni M, Pansiot J, Colella M, Faivre V, Delahaye-Duriez A, Guillonneau F, Bruce J, Salnot V, Mairesse J, Knoop M, Possovre ML, Vaiman D, Baud O, Impact of Fetal Growth Restriction on the Neonatal Microglial Proteome in the Rat. Nutrients, 13(11):(2021) [pubmed] |
Keyword List
submitter keyword: microglia |
IUGR |
inflammation |
proteome |
brain development |
mass spectrometry |
Contact List
Olivier Baud |
contact affiliation | Université de Paris, Inserm UMR 1141 NeuroDiderot, F-75019Paris |
contact email | olivier.baud@hcuge.ch |
lab head | |
Virginie Salnot |
contact affiliation | 3p5-proteom'ic plateform |
contact email | virginie.salnot@parisdescartes.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD028950
- Label: PRIDE project
- Name: Impact of fetal growth restriction on neonatal microglia proteome in rat.