PXD028928 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Long-term nutritional regulation of liver proteome |
Description | Nutrient sensing pathways influence metabolic health and aging, offering the possibility that diet might be used therapeutically, alone or with drugs targeting these pathways. We used the Geometric Framework for Nutrition to study interactive and comparative effects of diet and drugs on the hepatic proteome in mice across 40 dietary treatments differing in macronutrient ratios, energy density, and drug treatment (metformin, rapamycin, resveratrol). |
HostingRepository | PRIDE |
AnnounceDate | 2021-12-13 |
AnnouncementXML | Submission_2021-12-12_21:30:42.109.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Benjamin Parker |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-10-04 10:02:01 | ID requested | |
⏵ 1 | 2021-12-12 21:30:42 | announced | |
Publication List
Le Couteur DG, Solon-Biet SM, Parker BL, Pulpitel T, Brandon AE, Hunt NJ, Wali JA, Gokarn R, Senior AM, Cooney GJ, Raubenheimer D, Cogger VC, James DE, Simpson SJ, Nutritional reprogramming of mouse liver proteome is dampened by metformin, resveratrol, and rapamycin. Cell Metab, 33(12):2367-2379.e4(2021) [pubmed] |
Keyword List
submitter keyword: liver, proteomics, Metformin, rapamycin, resveratrol, diet |
Contact List
Benjamin Parker |
contact affiliation | The University of Melbourne |
contact email | ben.parker@unimelb.edu.au |
lab head | |
Benjamin Parker |
contact affiliation | The University of Melbourne |
contact email | ben.parker@unimelb.edu.au |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/12/PXD028928 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD028928
- Label: PRIDE project
- Name: Long-term nutritional regulation of liver proteome