PXD028790-1

PXD028790 is an original dataset announced via ProteomeXchange.

Title	TMT quantitative proteomic analysis of craniopharyngioma tissues
Description	Craniopharyngiomas are rare epithelial tumors derived from pituitary gland embryonic tissue. This epithelial tumor entity can be divided into the adamantinomatuous (ACP) and papillary (PCP) subtypes with the histomorphological and genetic differences. Genomic and transcriptomic profiles of craniopharyngiomas have been investigated, however the proteomic contribution to these profiles has yet to be elucidated. Recent improvement in high-throughput quantitative proteomic approaches have introduced new opportunities for a better understanding of these disease and an efficient discovering of biomarkers. In this study, we report a systems-level proteomic study of sub-type associated proteome changes in six specimens of ACP and five specimens of PCP using an integrated approach that combines mass spectrometry-based quantitative proteomics, statistical analysis, and bioinformatics analysis.
HostingRepository	PRIDE
AnnounceDate	2022-02-16
AnnouncementXML	Submission_2022-02-16_13:52:59.255.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dohyun Han
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2021-09-27 06:50:10	ID requested
⏵ 1	2022-02-16 13:53:00	announced

Kim JH, Kim H, Dan K, Kim SI, Park SH, Han D, Kim YH, In-depth proteomic profiling captures subtype-specific features of craniopharyngiomas. Sci Rep, 11(1):21206(2021) [pubmed]

submitter keyword: Human, Craniopharyngioma, TMT, LC-MS/MS

Dohyun han
contact affiliation	Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital
contact email	hdh03@snu.ac.kr
lab head
Dohyun Han
contact affiliation	Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital
contact email	hdh03@snu.ac.kr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD028790

PRIDE project URI

• PRIDE
  1. PXD028790
     1. Label: PRIDE project
     2. Name: TMT quantitative proteomic analysis of craniopharyngioma tissues