PXD028702-2

PXD028702 is an original dataset announced via ProteomeXchange.

Title	Protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls
Description	Using liquid chromatography combined with tandem mass spectrometry, we want to use quantitative proteomics of CD4+ T cells from relapsing-remitting MS (RRMS) patients and healthy controls. Cells were left unstimulated or stimulated through the T cell receptor (TCR) in vitro allowing us to disentangle potential CD4+ T cell specific differences induced by T cell activation This will provide novel insights into disease mechanisms of MS.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:53:31.421.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD028702
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Tone Berge
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-09-22 12:10:27	ID requested
1	2022-08-01 05:39:51	announced
⏵ 2	2023-11-14 08:53:31	announced	2023-11-14: Updated project metadata.

10.6019/PXD028702;

submitter keyword: Autoimmunity, T cell activation, proteomics, multiple sclerosis, disease susceptibility genes

Tone Berge
contact affiliation	Department of Mechanical, Electronics and Chemical Engineering, Faculty of Technology, Art and Design, OsloMet - Oslo Metropolitan University, Postboks 4, St. Olavs Plass, 0130 Oslo, Norway
contact email	tone.berge@medisin.uio.no
lab head
Tone Berge
contact affiliation	Oslo University Hospital
contact email	tone.berge@medisin.uio.no
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD028702

PRIDE project URI

• PRIDE
  1. PXD028702
     1. Label: PRIDE project
     2. Name: Protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls