PXD028419-1

PXD028419 is an original dataset announced via ProteomeXchange.

Title	Cannabidiol displays proteomic similarities to antipsychotics in cuprizone-exposed human oligodendrocytic cell line MO3.13
Description	We employed nano-chromatography coupled with mass spectrometry to investigate the proteomic response to benztropine,cannabidiol, clozapine, and haloperidol, both in healthy oligodendrocytic cells and in a cuprizone-based toxicity model, using the human oligodendrocyte precursor cell line MO3.13.
HostingRepository	PRIDE
AnnounceDate	2021-11-11
AnnouncementXML	Submission_2021-11-11_14:45:24.743.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ana Caroline Brambilla Falvella
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2021-09-09 13:45:33	ID requested
⏵ 1	2021-11-11 14:45:25	announced

Falvella ACB, Smith BJ, Silva-Costa LC, Valen, ç, a AGF, Crunfli F, Zuardi AW, Hallak JE, Crippa JA, de Almeida V, Martins-de-Souza D, Cannabidiol Displays Proteomic Similarities to Antipsychotics in Cuprizone-Exposed Human Oligodendrocytic Cell Line MO3.13. Front Mol Neurosci, 14():673144(2021) [pubmed]

submitter keyword: benztropine, clozapine, haloperidol, MO3.13 cell line, phytocannabinoid, proteome, schizophrenia

Daniel Martins-de-Souza
contact affiliation	Laboratory of Neuroproteomics, Institute of Biology, UNICAMP (State University of Campinas), Brazil
contact email	dmsouza@unicamp.br
lab head
Ana Caroline Brambilla Falvella
contact affiliation	Unicamp
contact email	acfalvella@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD028419

PRIDE project URI

• PRIDE
  1. PXD028419
     1. Label: PRIDE project
     2. Name: Cannabidiol displays proteomic similarities to antipsychotics in cuprizone-exposed human oligodendrocytic cell line MO3.13