PXD028246 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Human HEK293T cells LC-MS/MS (Gel-based proteomics) |
Description | Fanconi Anemia (FA) pathway is essential for the repair of inter-strand crosslink (ICLs). ICL induces stalled replication forks and triggers activation of FA pathway for efficient ICL repair. Given that stalled replication fork is proximal to ICLs sites, fork-associated proteins may likely coordinate with FA factors to rapidly sense ICLs for activation of FA signaling. We will use LC-MS/MS to identify such proteins that participated in the ICL repairs. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:45:52.782.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | YI ZHANG |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-09-09 07:57:13 | ID requested | |
1 | 2023-05-10 09:02:59 | announced | |
⏵ 2 | 2023-11-14 08:46:01 | announced | 2023-11-14: Updated project metadata. |
Publication List
Zhang Y, Li J, Zhou Y, Li Z, Peng C, Pei H, Zhu W, And-1 Coordinates with the FANCM Complex to Regulate Fanconi Anemia Signaling and Cisplatin Resistance. Cancer Res, 82(18):3249-3262(2022) [pubmed] |
Keyword List
submitter keyword: Fanconi Anemia Pathway,Human cells, WDHD1 |
Contact List
Wenge Zhu |
contact affiliation | The George Washington University, Department of Biochemisty and Molecular Medicine, Cacncer Center, D.C., 20037 |
contact email | wz6812@gwu.edu |
lab head | |
YI ZHANG |
contact affiliation | The George Washington University |
contact email | scholarzy@gwu.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD028246 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD028246
- Label: PRIDE project
- Name: Human HEK293T cells LC-MS/MS (Gel-based proteomics)