PXD027983-1
PXD027983 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Houles et al_BioID analysis of ERK1 and ERK2_2021 |
| Description | This dataset consists of 11 raw MS files and associated peak lists and result files, acquired on an Orbitrap Fusion mass spectrometer operated in Data Dependent Acquisition mode. The files are associated with a manuscript submitted for publication by Thibault Houles et al. titled: CDK12 is hyperactivated and a prime synthetic-lethal target in BRAF-mutated melanoma. The manuscript defines the proximity interactome of ERK1 and ERK2 kinases in HEK293 cells, and the consequences of ERK1/2-mediated CDK12 phosphorylation. Experiments are proximity-dependent biotinylation (BioID), all performed in biological triplicates with associated negative controls. Philippe Roux is the corresponding author of the manuscript philippe.roux at umontreal.ca. |
| HostingRepository | MassIVE |
| AnnounceDate | 2022-08-30 |
| AnnouncementXML | Submission_2022-08-30_12:28:30.546.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Philippe Roux |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2021-08-17 08:43:42 | ID requested | |
| ⏵ 1 | 2022-08-30 12:28:30 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: proximity-dependent biotinylation, BioID, kinases, ERK1, ERK2 |
Contact List
| Philippe Roux | |
|---|---|
| contact affiliation | Universite de Montreal |
| contact email | philippe.roux@umontreal.ca |
| lab head | |
| Philippe Roux | |
| contact affiliation | IRIC |
| contact email | philippe.roux@umontreal.ca |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000087994/ |
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