PXD027965-1

PXD027965 is an original dataset announced via ProteomeXchange.

Title	Alterations of protein S-glutathionylation modification in macrophages under oxidative conditions
Description	S-glutathionylation is an important regulatory posttranslational modification of protein cysteine (Cys) thiols, yet the role of specific cysteine residues as targets of modification is poorly understood. To identify the specific molecular targets and pathways of Grx1 that are susceptible to redox-dependent regulation, we applied a quantitative redox proteomics approach that permits site-specific profiling of S-glutathionylation at a proteome-wide scale in macrophages.
HostingRepository	PRIDE
AnnounceDate	2021-11-01
AnnouncementXML	Submission_2021-11-01_04:43:08.588.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuxian Guo
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	L-cysteine glutathione disulfide
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2021-08-17 04:05:11	ID requested
⏵ 1	2021-11-01 04:43:08	announced

Dataset with its publication pending

submitter keyword: BMDM, S-glutathionylation,LC–MS/MS

Xue Zhang
contact affiliation	Zhejiang University School of Medicine
contact email	zhangxue@zju.edu.cn
lab head
Yuxian Guo
contact affiliation	Zhejiang University School of Medicine
contact email	yuxian_guo@zju.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD027965

PRIDE project URI

• PRIDE
  1. PXD027965
     1. Label: PRIDE project
     2. Name: Alterations of protein S-glutathionylation modification in macrophages under oxidative conditions