PXD027840-1

PXD027840 is an original dataset announced via ProteomeXchange.

Title	HSP70-driven molecular response to the proteasome machinery inhibition is a vulnerability in cancer
Description	Two human primary fibroblast cell lines indicated in the file names were either treated with carfilzomib (C) at the concentrations near the IC50 of proteasome activity (10nM) for 24h, or with DMSO (D) as a control, in biological duplicates (numbers 1-2).
HostingRepository	PRIDE
AnnounceDate	2025-10-29
AnnouncementXML	Submission_2025-10-29_04:37:15.361.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jacek Wisniewski
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-08-10 00:09:23	ID requested
⏵ 1	2025-10-29 04:37:15	announced

10.1016/J.CELREP.2022.111428;

submitter keyword: Human, cell lines, fibroblasts

Jacek R. Wisniewski
contact affiliation	Max Planck Institute of Biochemistry. Dept Proteomics and Signal Transduction. Martinsried, Germany
contact email	jwisniew@biochem.mpg.de
lab head
Jacek Wisniewski
contact affiliation	Proteomics
contact email	jwisniew@biochem.mpg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD027840

PRIDE project URI

• PRIDE
  1. PXD027840
     1. Label: PRIDE project
     2. Name: HSP70-driven molecular response to the proteasome machinery inhibition is a vulnerability in cancer