PXD027239 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Metabolic labeling of NMT substrates by photoactivatable/clickable myristate probes X3/X8/X10 |
Description | Efficiency of labelling by photoactivatable/clickable myristate probes X3/X8/X10 is compared to the positive control probe YnMyr. Additionally, negative controls for each probe were obtained by treatment with NMT ihibitor IMP-366 (DDD85464). The resulting data indicates efficient labeling of NMT substrates by photoactivatable probes that is NMT-dependent. |
HostingRepository | PRIDE |
AnnounceDate | 2023-03-11 |
AnnouncementXML | Submission_2023-03-10_23:47:51.367.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | RomanFedoryshchak |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | myristoylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-07-12 01:43:20 | ID requested | |
⏵ 1 | 2023-03-10 23:47:52 | announced | |
2 | 2023-11-14 08:38:45 | announced | 2023-11-14: Updated project metadata. |
Publication List
Fedoryshchak RO, Gorelik A, Shen M, Shchepinova MM, P, é, rez-Dorado I, Tate EW, Discovery of lipid-mediated protein-protein interactions in living cells using metabolic labeling with photoactivatable clickable probes. Chem Sci, 14(9):2419-2430(2023) [pubmed] |
Keyword List
submitter keyword: NMT, diazirine, metabolic labeling, myristoylation, photocrosslinking |
Contact List
EdwardTate |
contact affiliation | Professor of Chemical Biology, Imperial College London Satellite Group Leader, Francis Crick Institute Founder & SAB, Myricx Pharma Ltd Room 301B, Molecular Sciences Research Hub, White City Campus 82 Wood Lane, London W12 0BZ, UK |
contact email | e.tate@imperial.ac.uk |
lab head | |
RomanFedoryshchak |
contact affiliation | The Francis Crick Institute |
contact email | roman.fedoryshchak@crick.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD027239 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD027239
- Label: PRIDE project
- Name: Metabolic labeling of NMT substrates by photoactivatable/clickable myristate probes X3/X8/X10