PXD027125-1

PXD027125 is an original dataset announced via ProteomeXchange.

Title	Plasma biomarkers for aortic dilation in BAV patients
Description	Bicuspid aortic valve (BAV) is the most common congenital heart anomaly and is prone to cause complications, such as valvular stenosis and thoracic aortic dilation. There is currently no reliable way to predict the progression rate to thoracic aortic aneurysm. Here, we aimed to characterize the proteomic landscape in the plasma of stenotic BAV patients and provide potential biomarkers to predict progressive aortic dilation. Plasma samples were obtained from 45 subjects (30 stenotic BAV patients and 15 healthy controls). All samples were properly prepared and analyzed using mass spectrometry (MS)-based label-free quantitative proteomics.
HostingRepository	PRIDE
AnnounceDate	2021-08-19
AnnouncementXML	Submission_2021-08-19_03:33:21.520.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhang Weijia
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-06 01:24:06	ID requested
⏵ 1	2021-08-19 03:33:21	announced

Dataset with its publication pending

submitter keyword: bicuspid aortic valve, aortic dilation, plasma, LC-MS/MS

Weijia Zhang
contact affiliation	Fudan University
contact email	weijiazhang@fudan.edu.cn
lab head
Zhang Weijia
contact affiliation	Fudan University
contact email	weijiazhang@fudan.edu.cn
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD027125
     1. Label: PRIDE project
     2. Name: Plasma biomarkers for aortic dilation in BAV patients