PXD027078-1
PXD027078 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Differences of phosphoproteome between c-MYC and L-MYC during cellular reprogramming |
Description | MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed proteome analysis to tackle this question and found MYC Box 0 (MB0) and 2 (MB2), one of the functional domains conserved in MYC family protein, might cause the phenotypic differences between the MYC proteins. |
HostingRepository | jPOST |
AnnounceDate | 2022-01-08 |
AnnouncementXML | Submission_2022-01-07_07:00:13.496.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Iwasaki Mio |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; deamidated L-asparagine; deamidated L-glutamine; 2-pyrrolidone-5-carboxylic acid (Glu); 2-pyrrolidone-5-carboxylic acid (Gln); alpha-amino acetylated residue; Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-07-02 23:56:40 | ID requested | |
⏵ 1 | 2022-01-07 07:00:14 | announced | |
2 | 2022-09-18 03:14:49 | announced | 2022-09-18: Updated FTP location. |
Publication List
Akifuji C, Iwasaki M, Kawahara Y, Sakurai C, Cheng YS, Imai T, Nakagawa M, MYCL promotes iPSC-like colony formation via MYC Box 0 and 2 domains. Sci Rep, 11(1):24254(2021) [pubmed] |
Keyword List
submitter keyword: MYC, reprogramming, proteome |
Contact List
Mio Iwasaki | |
---|---|
lab head | |
Iwasaki Mio | |
contact affiliation | Kyoto University |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.biosciencedbc.jp/archive/jpostrepos/JPST001237 |