PXD026926 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Interactome of a TurboID-tagged BRD9 in the presence or absence of IFN-a2 |
Description | BRD9 was identified in a genome-wide screen for genes regulating the response to interferon (IFN) in a A549 based reporter cell line. Subsequent experiments determined an involvement of BRD9 in the transcriptional regulation of Interferon-stimulated genes (ISGs) expression following stimulation with IFN-a2. The aim of this proximity-labelling experiments was to gain a more mechanistic understanding of BRD9 recruitment during the IFN signal transduction using A549 cells stably transduced with BRD9-TurboID and mCherry-TurboID fusion proteins. The BRD9 interactome in the absence of IFN- a2 was determined. We found that following IFN-a2 treatment, STAT2 significantly associates with BRD9-TurboID. |
HostingRepository | PRIDE |
AnnounceDate | 2021-08-17 |
AnnouncementXML | Submission_2021-08-17_03:03:26.676.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jacob Börold |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | biotinylated residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-06-24 23:54:48 | ID requested | |
⏵ 1 | 2021-08-17 03:03:27 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: TurboID, BRD9, A549, STAT2, BRD9-TurboID, proximity labeling, IFN-signalling |
Contact List
Benjamin Geoffrey Hale |
contact affiliation | University of Zurich, Institute for Medical Virology, Switzerland |
contact email | hale.ben@virology.uzh.ch |
lab head | |
Jacob Börold |
contact affiliation | University of Zurich |
contact email | boerold.jacob@virology.uzh.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD026926 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD026926
- Label: PRIDE project
- Name: Interactome of a TurboID-tagged BRD9 in the presence or absence of IFN-a2