PXD026892-1
PXD026892 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies |
Description | KRAS mutant cancers, which feature the activation of multiple phosphorylation signaling pathways, remain a major challenge for cancer therapy. This study provides a landscape of the proteomics and phosphoproteomics of KRAS mutant cancers by analyzing different KRAS mutant human cancer cell lines across different tissues types. By integrating multi-omics analysis, we identify different robust subsets, which recapitulate the histological, pathological and prognostic features of human cancers. |
HostingRepository | iProX |
AnnounceDate | 2021-06-23 |
AnnouncementXML | Submission_2021-07-29_00:34:32.194.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Linhui Zhai |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-06-23 19:52:17 | ID requested | |
⏵ 1 | 2021-07-29 00:34:32 | announced | |
2 | 2023-08-27 21:05:42 | announced | 2023-08-28: Update publication information. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: KRAS, proteomics, phosphoproteomics |
Contact List
Minjia Tan | |
---|---|
contact affiliation | Shanghai Institute of Materia Medica |
contact email | mjtan@simm.ac.cn |
lab head | |
Linhui Zhai | |
contact affiliation | Shanghai Institute of Materia Medica |
contact email | zhailinhui@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |