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PXD026837-2

PXD026837 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentification of PTB ΔNLS-GFP interacting proteins precipitated by magnetic beads against GFP
DescriptionThe purpose of the study was to determine proteins that specially interact cytoplasmic PTB. PTB is an RNA binding protein that shuttles between the nucleus and cytoplasm. To identified proteins interacting with cytoplasmic PTB, nucleus localization signal was deleted (PTB ΔNLS-GFP) and overexpressed followed by IP and MS.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:32:42.495.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFuxing Gong
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-06-21 03:04:36ID requested
12022-02-17 04:43:36announced
22024-10-22 05:32:44announced2024-10-22: Updated project metadata.
Publication List
10.1093/nar/gkab708;
Gong FX, Zhan G, Han R, Yang Z, Fu X, Xiao R, De-dimerization of PTB is catalyzed by PDI and is involved in the regulation of p53 translation. Nucleic Acids Res, 49(16):9342-9352(2021) [pubmed]
Keyword List
submitter keyword: PTB
Contact List
Fuxing Gong
contact affiliationResearch Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
contact emailfxgong@sina.com
lab head
Fuxing Gong
contact affiliationResearch Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
contact emailfxgong@sina.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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