PXD026658 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Surface proteome of large extracellular vesicles |
Description | The extracellular vesicle (EV) surface proteome (surfaceome) acts as a fundamental signalling gateway by bridging intra-and extracellular signalling networks, dictates EVs’ capacity to communicate and interact with its the/their environment, and is a source of potential disease biomarkers and therapeutic targets. However, our understanding of surface protein composition of large EVs (100-1000 nm), a major EV-subtype remains limited. Our study provides critical insights into proteins operating at the large interactive platform of L-EVs, and molecular leads for future studies seeking to decipher relatively-understudied L-EV form, heterogeneity and function. |
HostingRepository | PRIDE |
AnnounceDate | 2021-11-17 |
AnnouncementXML | Submission_2021-11-17_09:02:17.465.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | david greening |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | biotinylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-06-11 07:24:56 | ID requested | |
⏵ 1 | 2021-11-17 09:02:17 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Surface, interactome, extracellular vesicles, proteomics, large extracellular vesicles |
Contact List
David Greening |
contact affiliation | Baker Heart and Diabetes Institute |
contact email | david.greening@baker.edu.au |
lab head | |
david greening |
contact affiliation | Baker Heart and Diabetes Inst. |
contact email | david.greening@baker.edu.au |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD026658 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD026658
- Label: PRIDE project
- Name: Surface proteome of large extracellular vesicles