PXD026620-1
PXD026620 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Cardiolipin remodeling enables protein crowding in the inner mitochondrial membrane |
| Description | Mitochondrial cristae are more crowded with proteins than other cellular membranes. However, protein crowding stresses the bilayer organization of lipids, which challenges membrane stability. We tested the hypothesis that the high concentration of proteins drives the tafazzin-catalyzed remodeling of fatty acids in cardiolipin (CL) to reduce stress on the lipid bilayer |
| HostingRepository | MassIVE |
| AnnounceDate | 2021-07-26 |
| AnnouncementXML | Submission_2021-07-26_07:49:39.494.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Hediye Erdjument-Bromage |
| SpeciesList | scientific name: Drosophila melanogaster; common name: fruit fly; NCBI TaxID: 7227; scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090; scientific name: Saccharomyces cerevisiae; common name: baker's yeast; NCBI TaxID: 4932; |
| ModificationList | unknown modification |
| Instrument | Q Exactive; Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2021-06-10 08:43:41 | ID requested | |
| ⏵ 1 | 2021-07-26 07:49:39 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Barth syndrome, lipids, lipid-protein interaction, macromolecular crowding, mitochondria, oxidative phosphorylation |
Contact List
| Dr. Thomas A. Neubert | |
|---|---|
| contact affiliation | New York University School of Medicine |
| contact email | Thomas.Neubert@med.nyu.edu |
| lab head | |
| Dr. Michael Schlame | |
| contact affiliation | New York University School of Medicine |
| contact email | michael.schlame@med.nyu.edu |
| lab head | |
| Hediye Erdjument-Bromage | |
| contact affiliation | New York University School of Medicine |
| contact email | Hediye.Bromage@med.nyu.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000087602/ |
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