PXD026358-1

PXD026358 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mass spectrometry-based direct detection of multiple types of protein thiol modifications in pancreatic beta cells under endoplasmic reticulum stress
Description	A 2D-LC-MS/MS strategy coupled with TMT-10 labeling was applied to mouse pancreatic beta cells (hetaTC-6) induced with ER stress by Thapsigargin to study the global proteome and protein cysteine PTM changes under ER stress. Samples were digested with trypsin, labeled with 10-plex TMT, then analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's DMS processing pipeline
HostingRepository	MassIVE
AnnounceDate	2022-08-16
AnnouncementXML	Submission_2022-08-16_09:11:31.462.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Matthew Monroe
SpeciesList	scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationList	TMT6plex; Oxidation; Glutathione; Dioxidation; Trioxidation; Dehydro; Nitrosyl; unknown modification
Instrument	Q Exactive HF-X

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-29 20:39:16	ID requested
⏵ 1	2022-08-16 09:11:31	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Redox PTMs, pancreatic beta cells, ER stress

submitter keyword: Redox PTMs, pancreatic beta cells, ER stress

Contact List

Wei-Jun Qian
contact affiliation	Pacific Northwest National Laboratory
contact email	Weijun.Qian@pnnl.gov
lab head
Matthew Monroe
contact affiliation	Pacific Northwest National Laboratory
contact email	matthew.monroe@pnnl.gov
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000087543/