PXD026095 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The human and mouse islet peptidome: effects of obesity and type 2 diabetes |
| Description | To characterise the impact of metabolic disease on the peptidome of human and mouse pancreatic islets and the contribution of intra-islet glucagon-like peptide 1 (GLP-1) receptor signalling. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-10-22 |
| AnnouncementXML | Submission_2024-10-22_05:24:50.146.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD026095 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Richard Kay |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | amidated residue; 2-pyrrolidone-5-carboxylic acid (Gln); acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2021-05-19 09:00:15 | ID requested | |
| 1 | 2021-08-24 07:03:48 | announced | |
| 2 | 2021-08-25 00:39:08 | announced | 2021-08-25: Updated project metadata. |
| ⏵ 3 | 2024-10-22 05:24:51 | announced | 2024-10-22: Updated project metadata. |
Publication List
| 10.6019/PXD026095; |
| 10.1021/acs.jproteome.1c00463; |
| Galvin SG, Kay RG, Foreman R, Larraufie P, Meek CL, Biggs E, Ravn P, Jermutus L, Reimann F, Gribble FM, The Human and Mouse Islet Peptidome: Effects of Obesity and Type 2 Diabetes, and Assessment of Intraislet Production of Glucagon-like Peptide-1. J Proteome Res, 20(9):4507-4517(2021) [pubmed] |
Keyword List
| submitter keyword: peptidomics, type 2 diabetes, glucagon, islets, insulin |
Contact List
| Professor Fiona Gribble |
|---|
| contact affiliation | Wellcome Trust MRC Institute of Metabolic Science |
| contact email | fmg23@cam.ac.uk |
| lab head | |
| Richard Kay |
|---|
| contact affiliation | University of Cambridge |
| contact email | rgk27@medschl.cam.ac.uk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD026095 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD026095
- Label: PRIDE project
- Name: The human and mouse islet peptidome: effects of obesity and type 2 diabetes
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