PXD026086-2

PXD026086 is an original dataset announced via ProteomeXchange.

Title	The Human Melanoma Proteome Atlas – Defining the Molecular Pathology & Complementing the Melanoma Transcriptome
Description	This project is an initiative to map the protein levels in malignant melanoma tumor samples, focused on in-depth histopathology coupled to proteome characterization. The protein levels and localization from this project were determined for a broad spectrum of diverse, surgically isolated melanoma tumors originating from multiple body locations. In this study, the quantitative mass-spectrometry-based proteomic analysis is interfaced with pathological tumor characterization, and associated with clinical data. All proteoforms and the generated data were identified by mass spectrometry and global proteomic experiments, from which chromosomal and sub-cellular localization was annotated within both primary and metastatic melanoma.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:53:08.250.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yonghyo Kim
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	carbamoylated residue; acetylated residue; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF; Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-19 03:28:48	ID requested
1	2021-07-16 06:42:10	announced
⏵ 2	2023-11-14 08:53:08	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: proteogenomics, histopathology, heterogeneity, BRAF, phosphorylation, driver mutations,Metastatic malignant melanoma, sub-cellular localization, acetylation stoichiometry, post-translational-modification

Gyorgy Marko-Varga
contact affiliation	Division of Clinical Protein Science & Imaging, Department of Clinical Sciences (Lund), Department of Biomedical Engineering, Lund University, Lund, Sweden
contact email	gyorgymarkovarga@hotmail.com
lab head
Yonghyo Kim
contact affiliation	Lund University, Faculty of Medicine
contact email	duk0295@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD026086

PRIDE project URI

• PRIDE
  1. PXD026086
     1. Label: PRIDE project
     2. Name: The Human Melanoma Proteome Atlas – Defining the Molecular Pathology & Complementing the Melanoma Transcriptome