PXD025885 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | IgG from systemic sclerosis patients induce a profibrosing and serotype-dependent phenotype in normal dermal fibroblast: a multi-omics study |
Description | Autoantibodies (Aab) are frequent in systemic sclerosis (SSc). While recognized as potent biomarkers, their pathogenic role is much debated. This study explored the effect of purified IgG from SSc patients on the phenotype and function of healthy dermal fibroblast (FB) using an innovative multi-omics approach. |
HostingRepository | PRIDE |
AnnounceDate | 2022-06-29 |
AnnouncementXML | Submission_2022-06-29_04:40:39.634.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | BRAY FABRICE |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-05-07 09:46:21 | ID requested | |
⏵ 1 | 2022-06-29 04:40:40 | announced | |
2 | 2023-11-14 08:52:40 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: Systemic sclerosis, Sensitive proteomic, Multi-omics analysis, Autoantibodies, Anti-topoisomerase type I |
Contact List
Vincent Sobanski |
contact affiliation | Univ. Lille, U1286 – INFINITE – Institute for Translational Research in Inflammation, F59000 Lille, France |
contact email | vincent.sobanski@univ-lille.fr |
lab head | |
BRAY FABRICE |
contact affiliation | MSAP USR 3290 |
contact email | fabrice.bray@univ-lille.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/06/PXD025885 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD025885
- Label: PRIDE project
- Name: IgG from systemic sclerosis patients induce a profibrosing and serotype-dependent phenotype in normal dermal fibroblast: a multi-omics study