PXD025662-2

PXD025662 is an original dataset announced via ProteomeXchange.

Title	Molecular architecture of the human tRNA ligase complex
Description	Chemical cross-linking coupled to mass spectrometry was used to study two tRNA ligase complexes, one consisting of subunits RTCB, DDX1, CGI-99, FAM98B and Ashwin (“full tRLC”) and one lacking Ashwin (“core tRLC”). Cross-linking was performed using the homobifunctional, noncleavable reagent, disuccinimidyl suberate (DSS).
HostingRepository	PRIDE
AnnounceDate	2021-12-15
AnnouncementXML	Submission_2021-12-20_11:33:31.822.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alexander Leitner
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-27 08:33:46	ID requested
1	2021-12-15 02:28:57	announced
⏵ 2	2021-12-20 11:33:32	announced	2021-12-20: Updated publication reference for PubMed record(s): 34854379.

Kroupova A, Ackle F, Asanovi, ć I, Weitzer S, Boneberg FM, Faini M, Leitner A, Chui A, Aebersold R, Martinez J, Jinek M, Molecular architecture of the human tRNA ligase complex. Elife, 10():(2021) [pubmed]

submitter keyword: Chemical cross-linking

DSS

structural proteomics

protein complex

tRNA ligase complex

Martin Jinek
contact affiliation	Department of Biochemistry, University of Zurich, Zurich, Switzerland
contact email	jinek@bioc.uzh.ch
lab head
Alexander Leitner
contact affiliation	ETH Zurich, Institute of Molecular Systems Biology
contact email	leitner@imsb.biol.ethz.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/12/PXD025662

PRIDE project URI

• PRIDE
  1. PXD025662
     1. Label: PRIDE project
     2. Name: Molecular architecture of the human tRNA ligase complex