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PXD025486-2

PXD025486 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMouse brain MALDI-imaging proteomics profiling
DescriptionWe developed and validated ‘HIT-MAP’ (High-resolution Informatics Toolbox in MALDI-MSI Proteomics), an open-source bioinformatics workflow using peptide mass fingerprint analysis and a dual scoring system to computationally assign peptide and protein annotations to high mass resolution MSI datasets, and generate customisable spatial distribution maps. The uploaded files are an example dataset for the HiTMaP proteomics search engine, designed for MALDI-imaging proteomics annotation. The example data files contain one bovine lens tissue section and one mouse brain tissue section. The ID folder contains the protein/peptide identification result for each tissue segment, and the summary folder contains the protein cluster images.
HostingRepositoryPRIDE
AnnounceDate2021-05-17
AnnouncementXMLSubmission_2021-07-19_23:22:47.875.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGUANGYU GUO
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationListNo PTMs are included in the dataset
InstrumentBruker Daltonics solarix series
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-20 02:16:11ID requested
12021-05-16 17:50:15announced
22021-07-19 23:22:48announced2021-07-20: Updated publication reference for PubMed record(s): 34050164.
32024-10-22 05:21:59announced2024-10-22: Updated project metadata.
Publication List
Guo G, Papanicolaou M, Demarais NJ, Wang Z, Schey KL, Timpson P, Cox TR, Grey AC, Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP. Nat Commun, 12(1):3241(2021) [pubmed]
Keyword List
submitter keyword: Mouse brain, MALDI-imaging, proteomics, bovin lens
Contact List
GUS GREY
contact affiliationDepartment of Physiology, the University of Auckland
contact emailac.grey@auckland.ac.nz
lab head
GUANGYU GUO
contact affiliationThe University of Auckland
contact emailguoguodigital@msn.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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