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PXD025213 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSupermeres, a new functional extracellular nanoparticle replete with disease biomarkers and therapeutic target
DescriptionExtracellular vesicles, including exosomes, and exomere nanoparticles, are under intense investigation for cargo that may serve as clinical biomarkers or therapeutic targets. Here, we report discovery of a new extracellular nanoparticle, termed supermeres. We performed LC/MS-MS proteomics analyses on gradient-purified sEVs, NVs, exomeres and supermeres. The proteomic profile of supermeres is clearly distinct from that of sEVs, NVs and exomeres This study identifies a new functional nanoparticle replete with potential circulating biomarkers and therapeutic targets that can be exploited for clinical benefit in a host of diseases.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKristie Lindsey Rose
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-06 07:09:51ID requested
12021-11-02 06:31:37announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Human, DiFi, sEV, exomere, supermere, colorectal cancer, LC-MS/MS
Contact List
Kristie Lindsey Rose
contact affiliationVanderbilt University
contact emailkristie.rose@vanderbilt.edu
lab head
Kristie Lindsey Rose
contact affiliationVanderbilt university
contact emailkristie.rose@vanderbilt.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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