PXD025128-2

PXD025128 is an original dataset announced via ProteomeXchange.

Title	Defining changes in the total levels of proteins during aging of C. elegans
Description	We performed label-free proteomics in C. elegans to define and quantify changes in the ubiquitinated (Ub)-proteome during the aging process. More specifically, we compared wild-type worms at the first day of adulthood with young (day 5), mid-age (day 10) and aged adults (day 15). Moreover, we assessed protein levels of age-matched long-lived genetic models of dietary restriction (eat-2(ad1116)) and reduced insulin/IGF-1 signaling (daf-2(e1370)).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:22:24.107.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	David Vilchez
SpeciesList	scientific name: Caenorhabditis elegans; NCBI TaxID: 6239;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-31 06:36:07	ID requested
1	2021-05-26 01:22:00	announced
⏵ 2	2024-10-22 05:22:24	announced	2024-10-22: Updated project metadata.
3	2024-11-11 06:16:11	announced	2024-11-11: Updated project metadata.

Dataset with its publication pending

submitter keyword: C. elegans,Proteome, aging

David Vilchez
contact affiliation	CECAD, University of Cologne
contact email	dvilchez@uni-koeln.de
lab head
David Vilchez
contact affiliation	University of Cologne
contact email	dvilchez@uni-koeln.de
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD025128
     1. Label: PRIDE project
     2. Name: Defining changes in the total levels of proteins during aging of C. elegans